Motherless Brooklyn is a Jonathan Lethem detective story set in Brooklyn and published in 1999. Lethem's protagonist, Lionel Essrog, has Tourette syndrome, a disorder marked by involuntary tics. Essrog works, along with Tony, Danny and Gilbert, who call themselves the Minna Men, for Frank Minna—a small-time neighborhood owner of a "seedy and makeshift" detective agency—who is stabbed to...